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 4.7 (1,600+ reviews)

Vet Recommended

Nepimi Yeast Reset + Itch Relief Drops

Nepimi Yeast Reset + Itch Relief Drops

check_circle Targets the gut–skin root cause of yeast overgrowth — not just surface-level symptoms

check_circle Made with 6 plant-based botanicals traditionally used to support microbial balance, skin comfort, and overall wellness

check_circle Fast-absorbing liquid tincture — easier than chews, with no fillers, no binders, and no fuss

check_circle Gentle daily support with no immune suppression — safe for long-term use across all ages and breeds

check_circle Bacon flavored and easy to add to food — no prescription required, no recurring vet bills

Nepimi Yeast Reset + Itch Relief Drops

Nepimi Yeast Reset + Itch Relief Drops

check_circle 90 Day Risk Free Guarantee

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  • Eco-Friendly

  • 90-Day Guarantee 

  • All Ages and Breeds

  • Liquid

  • 6 Botanicals

    What You’ve Tried vs. What Your Dog Actually Needs

    !

    What Most Dog Parents Try First

    • !

      Shampoos and sprays that only calm the surface for a few days

    • !

      Temporary symptom control while the gut–skin imbalance stays unresolved

    • !

      Repeated vet visits, messy routines, and costs that quickly add up

    • !

      Chews with fillers, binders, or ingredients picky dogs refuse to take

    What Your Dog’s Body Is Asking For

    • Daily inside-out support for the gut–skin connection

    • A gentle formula that supports natural microbial balance

    • 6 plant-based botanicals made for long-term daily use

    • Easy liquid drops with bacon flavor — no prescription required

    Dog parent comforting her dog

    Not Every Yeast Solution Works the Same Way.

    Most dog parents only treat what they can see — itchy skin, paw licking, odor, and irritation. But yeast-related issues can also be connected to internal gut balance, which surface products may never support.

    Nepimi is designed to support your dog from the inside out — not just cover up the outside symptoms.

    • Loose cells on the skin. What shampoos, sprays, and wipes target.

    • Protected by biofilm, up to 1,000× more resistant. Where yeast actually lives

      The inside-out protocol built to support where yeast imbalance begins.

      Most options only focus on what you can see. Nepimi Yeast Reset supports your dog’s gut–skin balance from within.

      Treatment
      Reach
      Outcome
      Medicated Shampoo
      (10%)
      Surface-level support only
      Topical Spray
      (20%)
      Temporary comfort, but signs may return
      Itch-Blocking Medication
      (30%)
      Targets itch response, not gut balance
      Antibiotics
      (40%)
      May disrupt good bacteria and internal balance
      Nepimi Yeast Reset
      (100%)
      Inside-out daily support for gut, skin comfort, and long-term balance

      Your dog’s yeast-related discomfort may show up on the skin, paws, ears, and coat — but lasting support starts with internal balance. Nepimi helps support the gut–skin connection from within

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        Support the Source

        Six plant-based botanicals help support your dog’s gut environment, where internal imbalance can begin.

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        Restore Daily Balance

        Helps maintain healthy gut pH, microbial balance, and normal digestive comfort.

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        Skin Reflects the Gut

        As internal balance improves, dogs may experience calmer skin, less paw licking, fresher odor, and a healthier-looking coat.

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        Maintain Long-Term Wellness

        Pair text withA simple daily routine designed to support ongoing gut, skin, and immune wellness over time. an icon to focus on your chosen product, collection, or blog post

        Why Nepimi’s 6-Botanical Formula Works From Different Angles

        Yeast-related discomfort can be connected to more than one imbalance. Nepimi combines complementary botanicals to support gut environment, skin comfort, digestion, and long-term daily balance.

        Pau D'Arco and Goldenseal botanicals

        Pau D’Arco + Goldenseal

        Microbial Balance Support

        These traditional botanicals help support a balanced internal microbial environment, giving your dog gentle daily support from the inside out.

        Apple cider vinegar and ginger root

        Apple Cider Vinegar + Ginger

        Gut Environment Support

        Apple cider vinegar helps support healthy gut pH, while ginger supports normal digestion, gut comfort, and a calmer internal response.

        Dandelion and marshmallow root botanicals

        Dandelion + Marshmallow Root

        Daily Repair & Comfort Support

        Dandelion supports natural liver and digestive function, while marshmallow root helps soothe and support the gut lining for daily comfort.

        Six botanicals. Three layers of support. One inside-out reset.

        Most yeast products rely on one ingredient and only address part of the problem. Nepimi uses a multi-botanical approach designed to support the way yeast-related imbalance can develop, persist, and come back.

        Support microbial balance. Improve the gut environment. Help the body recover.

        That’s why Nepimi is built to support your dog from the inside out — not just chase surface symptoms.

        What Should I Expect From Consistent Use?

        📅 1 Week - Calmer Routine

        Your dog may begin settling more comfortably as daily inside-out support starts building. Some owners notice less restless licking, chewing, or overnight scratching during this stage.*

        As gut and microbial balance receive consistent daily support, musty coat or paw odor may start becoming less noticeable. This is often when owners first feel the routine is helping.*

        📅 2 Weeks - Odor Support Begins
        📅 1 Month - Visible Comfort

        Paws may look calmer, ears may appear cleaner, and the coat may start looking healthier. This is the stage where consistent daily use can begin showing visible changes.*

        With continued support, your dog’s skin and coat may stay more comfortable between baths. The goal is to help maintain balance so small triggers do not turn into a full discomfort cycle.*

        📅 2 Months - Better Balance
        📅 3 Months - Full Reset Window

        By the 90-day mark, Nepimi has had time to support the gut–skin connection consistently. Many owners report a healthier-looking coat, calmer skin, and a more comfortable daily baseline.*

        Daily drops can help maintain long-term gut, skin, and immune wellness. Once your dog reaches a better baseline, consistency helps support that balance over time.*

        📅 6 Months - Maintenance Mode
        Results* vary by dog. Consistent daily use is the single biggest predictor of outcome.
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          Apoquel

          Helps reduce the itch response so your dog feels more comfortable short term. But it does not directly support the gut–skin balance behind recurring licking, odor, redness, or flare-ups.

        • check_circle

          Cytopoint

          A vet-administered injection designed to calm itching for a period of time. It may help with scratching, but many dogs still need ongoing support for the internal balance connected to skin and coat comfort.

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          Medicated Shampoos

          Can help wash away buildup on the skin and provide temporary freshness. But shampoos only work on the surface, so signs may return if your dog’s internal balance is not supported.

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          Antibiotics and Antifungals

          May be recommended by vets in certain cases, but repeated use can sometimes affect the gut microbiome. Supporting healthy gut balance is important for long-term skin, coat, and immune wellness.

          These treatments are usually designed to manage visible symptoms — not support the deeper gut–skin balance behind recurring discomfort.

          They may help your dog feel better for a while, but if the internal environment stays out of balance, the same licking, odor, scratching, and irritation can keep coming back.

          The better approach is supporting the gut–skin connection from within.

          With Nepimi’s plant-based botanicals, your dog gets daily support for microbial balance, digestive comfort, skin health, and long-term wellness.

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            Step 1: Shake Well

            Before every use to
            distribute evenly

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            Step 2: 3 to 10 drops

            Directly in mouth, mixed into food or water, or placed on a treat.

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            Step 3: Use Daily

            Best absorption between meals. Use consistently for 30 to 90 days.

            How Much Should I Give My Dog Daily?

            Simple daily dosing based on your dog’s size. Shake well before each use and give once daily.

            🐶

            Puppies & Toy Dogs

            Under 2.5 kg

            3 drops
            🐕

            Small Dogs

            5–10 kg

            5–6 drops
            🐕‍🦺

            Medium Dogs

            10–20 kg

            7–8 drops
            🦮

            Large Dogs

            Over 20 kg

            10 drops

            You can apply directly into the mouth, mix into food or water, or place on a small treat.

            Nepimi vs. The Rest

            See how Nepimi compares to common options many dog parents try first.

            NEPIMI Apoquel / Cytopoint
            Supports the gut–skin connection ×
            Plant-based botanical formula ×
            Designed for daily wellness support ×
            Easy liquid drops, no compressed chews ×
            No recurring injection visit required ×
            Gentle long-term routine for all breeds ×
            Supports skin, coat, gut, and immune wellness ×

            The Gut-First Formula Dog Parents Have Been Looking For

            More pet wellness experts are recognizing the connection between gut balance, skin comfort, and recurring yeast-related issues. Nepimi Yeast Reset was created around that same inside-out approach: support the gut environment first, so the skin and coat can follow.

            “I’ve been looking for a plant-based yeast support formula with clear dosing and a gut-first approach. Nepimi stands out because it’s simple, transparent, and designed for daily support.”

            Dr. Sandra B.
            Integrative Veterinarian

            • "Best $40 I've spent in three years of vet bills."

              "If you own a shepherd you know. The ears, the paws, the undercoat. When the yeast gets in, it gets everywhere. I'd tried three different medicated shampoos and two rounds of antifungals. The vet kept saying 'this is just part of the breed.' Natur was the first thing I found that went after the inside instead of the outside. Four weeks in, my wife said the house smelled different. Six weeks in, his skin stopped looking angry all the time. Still using it daily. Not stopping."

              David J

            • Finally stopped Googling 'why does my dog smell like corn chips at 2am.

              "I knew something was wrong but every vet visit ended with the same prescription. Apoquel worked for maybe three weeks, then we were back to square one and $200 poorer. I found Natur in a Reddit thread at 2am and figured I had nothing to lose. Week three, the smell was gone. Week five, she stopped chewing her paws through the night. I don't dread bath time anymore. I actually enjoy my dog again."

              Rachel T.

            • He's a happy pupper.

              "Every six weeks, $130. Every four weeks, she'd start scratching again before the next injection was even due. I knew I was paying to suppress something, not fix it. Natur took about six weeks to really show up. I won't pretend it was instant, but I'm now four months out from our last Cytopoint appointment. Her coat looks genuinely different. Shinier. Less greasy. And the house doesn't smell like a yeast infection anymore, which honestly I hadn't even fully admitted was happening""

              Marie D.

            • My vet never once said the word 'gut.'

              "Three years of recurring ear infections. Three years of medicated drops, chlorhexidine shampoo, and the same conversation at every appointment. When I read about the gut-skin connection, I felt genuinely angry. Why is this not the first thing they check? I started Natur on a whim, and by month two, his ears were cleaner than they'd been since he was a puppy. The bacon flavor meant zero fighting. He thinks it's a treat. I think it's the only thing that's actually worked."

              Sandra K.

              Comfort You Can Feel — Or It’s On Us

              Give Nepimi Yeast Reset a consistent 90-day try. If you don’t notice a meaningful improvement in your dog’s comfort, coat condition, or skin wellness, just contact us and we’ll refund you in full.

              No complicated returns. No hoops. Just daily support backed by our 90-day risk-free promise.

              Start My Dog’s 90-Day Reset →

              ✓ 90-Day Risk-Free Guarantee | 🚚 Ships in 1 Business Day

              Frequently Asked Questions

              How quickly will I see results?

              Most dog parents start noticing small changes within the first 2–4 weeks of consistent use. For dogs with ongoing skin, paw, ear, or odor concerns, the most noticeable improvements often happen with 60–90 days of daily support. Results can vary by dog.

              Is this safe for puppies and senior dogs?

              Yes. Nepimi is made for gentle daily support and can be used for dogs of all ages, from puppies to seniors. For very young puppies, pregnant dogs, nursing dogs, or dogs with existing medical conditions, check with your veterinarian first.

              Why drops instead of chews?

              Liquid drops are easy to mix into food, water, or treats, and they allow more flexible dosing based on your dog’s size. Unlike many compressed chews, Nepimi drops do not rely on bulky fillers or binders to hold their shape.

              What if my dog won’t take it?

              Most dogs take it easily when mixed with food, water, or a favorite treat. If your dog is picky, start with a smaller amount and gradually build up to the recommended daily dose.

              How long does one bottle last?

              A 60ml bottle typically lasts around 3–4 weeks, depending on your dog’s size and daily dose. For best results, we recommend consistent daily use for at least 60–90 days.

              My dog has an active yeast infection. Will this help?

              Nepimi is a dietary supplement designed to support gut balance, skin comfort, coat health, and daily wellness. It is not intended to diagnose, treat, cure, or prevent active infections. If your dog has a diagnosed infection or severe symptoms, please work with your veterinarian first.

              When will I receive my order?

              We ship within 24 hours after you place your order. And your order will be delivered within 4-6 business days! All orders come with a tracking number, insurance and loss protection.

              How can I contact Nepimi?

              You can contact our customer support team anytime by emailing us at info@nepimi.com. We’ll be happy to help with any questions about your order, product use, shipping, or returns.

              What is your return policy?

              We offer a 90-day free return policy. If you’re not fully satisfied with your order, simply contact us at info@nepimi.com and our support team will guide you through the return process.